Pseudorabies Virus Infections

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منابع مشابه

Pseudorabies Virus

Etiology • Pseudorabies virus (PRV) is an enveloped, double-stranded DNA virus belonging to the family Herpesviridae. Also known as suid herpesvirus-1 (SuHV-1), the virus causes Aujeszky’s disease. • ‘Classical’ PRV strains affecting multiple species were first isolated in the early 1900s. ‘Variant’ PRV strains emerged in swine in China in 2011. • Genomic sequencing and phylogenetic analyses ha...

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Pseudorabies Virus

Etiology • Pseudorabies virus (PRV) is an enveloped, double-stranded DNA virus belonging to the family Herpesviridae. Also known as suid herpesvirus-1 (SuHV-1), the virus causes Aujeszky’s disease. • ‘Classical’ PRV strains affecting multiple species were first isolated in the early 1900s. ‘Variant’ PRV strains emerged in swine in China in 2011. • Genomic sequencing and phylogenetic analyses ha...

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Cultivation of Pseudorabies Virus

Pseudorabies virus has been cultivated in series in rabbit testicle, guinea pig testicle, and chick embryo media, and its growth requirements have been studied. Intranuclear inclusions, similar to those produced by pseudorabies virus in vivo, have been found in rabbit testicle cultures. The virus has not changed its pathogenic properties for rabbits, guinea pigs, or mice during the course of cu...

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Pathogenic Pseudorabies Virus, China, 2012

In 2012, an unprecedented large-scale outbreak of disease in pigs in China caused great economic losses to the swine industry. Isolates from pseudorabies virus epidemics in swine herds were characterized. Evidence confirmed that the pathogenic pseudorabies virus was the etiologic agent of this epidemic.

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Characterization of Novel Transcripts in Pseudorabies Virus

In this study we identified two 3'-coterminal RNA molecules in the pseudorabies virus. The highly abundant short transcript (CTO-S) proved to be encoded between the ul21 and ul22 genes in close vicinity of the replication origin (OriL) of the virus. The less abundant long RNA molecule (CTO-L) is a transcriptional readthrough product of the ul21 gene and overlaps OriL. These polyadenylated RNAs ...

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ژورنال

عنوان ژورنال: Pathogens

سال: 2021

ISSN: 2076-0817

DOI: 10.3390/pathogens10060719